USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: BUB3_HUMAN USC-OGP 2-DE database:  BUB3_HUMAN BUB3_HUMAN General information about the entry View entry in simple text format Entry name BUB3_HUMAN Primary accession number O43684 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Mitotic checkpoint protein BUB3;. Gene name Name=BUB3 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1195: pI=6.77; Mw=40578 Cross-references UniProtKB/Swiss-Prot O43684; BUB3_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name BUB3_HUMAN Primary accession number O43684 Secondary accession number(s) A6NJ42 B2R6E7 D3DRE9 O43685 Sequence was last modified on  June 1, 1998 (version 1) Annotations were last modified on  March 15, 2017 (version 163) Name and origin of the protein Description RecName: Full=Mitotic checkpoint protein BUB3; Gene name Name=BUB3 Encoded on Name=BUB3 Keywords Acetylation; ADP-ribosylation; Alternative splicing; Cell cycle; Cell division; Centromere; Chromosome; Chromosome partition; Complete proteome; Isopeptide bond; Kinetochore; Meiosis; Mitosis; Nucleus; Phosphoprotein; Reference proteome; Repeat; Ubl conjugation; WD repeat. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AF047472; AAC28438.1; -; mRNA EMBL AF047473; AAC28439.1; -; mRNA EMBL AF053304; AAC06258.1; -; mRNA EMBL AF081496; AAC36307.1; -; mRNA EMBL AK312546; BAG35444.1; -; mRNA EMBL AC012391; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL CH471066; EAW49284.1; -; Genomic_DNA EMBL CH471066; EAW49285.1; -; Genomic_DNA EMBL CH471066; EAW49286.1; -; Genomic_DNA EMBL BC005138; AAH05138.1; -; mRNA EMBL BC022438; AAH22438.1; -; mRNA CCDS CCDS31306.1; -. [O43684-2]; . CCDS CCDS7635.1; -. [O43684-1]; . RefSeq NP_001007794.1; NM_001007793.2. [O43684-2]; . RefSeq NP_004716.1; NM_004725.3. [O43684-1]; . UniGene Hs.418533; -; . ProteinModelPortal O43684; -; . SMR O43684; -; . BioGrid 114621; 85; . DIP DIP-24205N; -; . IntAct O43684; 56; . MINT MINT-5005850; -; . STRING 9606.ENSP00000357858; -; . iPTMnet O43684; -; . PhosphoSitePlus O43684; -; . SwissPalm O43684; -; . BioMuta BUB3; -; . EPD O43684; -; . MaxQB O43684; -; . PaxDb O43684; -; . PeptideAtlas O43684; -; . PRIDE O43684; -; . TopDownProteomics O43684-1; -. [O43684-1]; . DNASU 9184; -; . Ensembl ENST00000368858; ENSP00000357851; ENSG00000154473. [O43684-2]; . Ensembl ENST00000368865; ENSP00000357858; ENSG00000154473. [O43684-1]; . GeneID 9184; -; . KEGG hsa:9184; -; . UCSC uc001lhd.3; human. [O43684-1]; . CTD 9184; -; . DisGeNET 9184; -; . GeneCards BUB3; -; . HGNC HGNC:1151; BUB3; . HPA CAB037075; -; . HPA HPA003601; -; . MalaCards BUB3; -; . MIM 603719; gene; . neXtProt NX_O43684; -; . OpenTargets ENSG00000154473; -; . Orphanet 1052; Mosaic variegated aneuploidy syndrome; . PharmGKB PA25467; -; . eggNOG KOG1036; Eukaryota; . eggNOG ENOG410XRBG; LUCA; . GeneTree ENSGT00530000063440; -; . HOGENOM HOG000208822; -; . HOVERGEN HBG002942; -; . InParanoid O43684; -; . KO K02180; -; . OMA EGEKSHE; -; . OrthoDB EOG091G0AB8; -; . PhylomeDB O43684; -; . TreeFam TF105454; -; . Reactome R-HSA-141430; Inactivation of APC/C via direct inhibition of the APC/C complex; . Reactome R-HSA-174184; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; . Reactome R-HSA-176409; APC/C:Cdc20 mediated degradation of mitotic proteins; . Reactome R-HSA-179409; APC-Cdc20 mediated degradation of Nek2A; . Reactome R-HSA-2467813; Separation of Sister Chromatids; . Reactome R-HSA-2500257; Resolution of Sister Chromatid Cohesion; . Reactome R-HSA-5663220; RHO GTPases Activate Formins; . Reactome R-HSA-68877; Mitotic Prometaphase; . SignaLink O43684; -; . ChiTaRS BUB3; human; . GeneWiki BUB3; -; . GenomeRNAi 9184; -; . PRO PR:O43684; -; . Proteomes UP000005640; Chromosome 10; . Bgee ENSG00000154473; -; . CleanEx HS_BUB3; -; . ExpressionAtlas O43684; baseline and differential; . Genevisible O43684; HS; . GO GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0000776; C:kinetochore; IDA:UniProtKB; . GO GO:0005654; C:nucleoplasm; IDA:HPA; . GO GO:0031145; P:anaphase-promoting complex-dependent catabolic process; TAS:Reactome; . GO GO:0008608; P:attachment of spindle microtubules to kinetochore; IDA:UniProtKB; . GO GO:0051301; P:cell division; IEA:UniProtKB-KW; . GO GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW; . GO GO:0000070; P:mitotic sister chromatid segregation; IEA:Ensembl; . GO GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome; . GO GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition; TAS:Reactome; . GO GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; TAS:Reactome; . GO GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; TAS:Reactome; . GO GO:0051983; P:regulation of chromosome segregation; IEA:Ensembl; . GO GO:0007062; P:sister chromatid cohesion; TAS:Reactome; . GO GO:0071173; P:spindle assembly checkpoint; IDA:UniProtKB; . Gene3D 2.130.10.10; -; 1; . InterPro IPR020472; G-protein_beta_WD-40_rep; . InterPro IPR015943; WD40/YVTN_repeat-like_dom; . InterPro IPR001680; WD40_repeat; . InterPro IPR017986; WD40_repeat_dom; . Pfam PF00400; WD40; 3; . PRINTS PR00320; GPROTEINBRPT; . SMART SM00320; WD40; 6; . SUPFAM SSF50978; SSF50978; 1; . PROSITE PS50082; WD_REPEATS_2; 2; . PROSITE PS50294; WD_REPEATS_REGION; 1; .

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